EK223

Mouse IL-23 ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

分子靶点：IL23A, IL-23, SGRF
种属：小鼠 (Mouse)
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：20 μL
灵敏度：0.31 pg/mL
检测范围：1.56 pg/mL - 100 pg/mL
回收率：80% - 99%

在售SKU:70-EK223-48, 70-EK223-96

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库存号

描述

文章目录[隐藏]

分子信息
IL23A 分子靶点信息概述
IL23A 分子靶点综述
- 小鼠 Mouse Il23a 分子靶点信息
- 小鼠 Mouse Il23a 靶点分子功能（预测）

商品名	Mouse IL-23 ELISA Kit (小鼠白细胞介素23 ELISA试剂盒)
检测方法	双抗夹心法
精密度	板内变异系数：3.0% - 5.4%；板间变异系数：4.4% - 6.4%
样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	20 μL
灵敏度	0.31 pg/mL
检测范围	1.56 pg/mL - 100 pg/mL
回收率	80% - 99%
平均回收率	0.91
板式	96孔板，可拆
保存	试剂盒未拆开，4℃保存。已拆开，标准品-20℃保存，其它4℃保存。
运输条件	4℃蓝冰运输
组分	包被抗IL-23单克隆抗体的96孔聚苯乙烯酶标板小鼠IL-23冻干标准品 IL-23检测抗体标准品稀释液检测缓冲液(10×) 底物(TMB) 终止液洗液(20×) 封板膜

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗小鼠IL-23抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的IL-23与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中IL-23的浓度成正比。加入终止液终止反应，在450 nm波长(参考波长570 - 630 nm)测定吸光度值。

Mouse IL-23 ELISA Kit (小鼠白细胞介素23 ELISA试剂盒) - 标准曲线 — 标准曲线

分子信息

概述小鼠 IL23A, IL-23, SGRF 靶点信息

IL23A 分子靶点信息概述

分子名：IL23A, interleukin 23 subunit alpha
基因家族：Interleukins
别名：SGRF; IL23P19; IL-23; IL-23A; P19
全称：interleukin-six, G-CSF related factor; interleukin 23, alpha subunit p19

IL23A 分子靶点综述

白细胞介素23(IL-23)是一种由IL-12p40亚基和IL-23p19亚基组成的异二聚体细胞因子，其中p40亚基是IL-23与IL-12共用的。IL-23的功能性受体已被鉴定，由IL-12Rβ1和IL-23R组成。IL-23在1型极化T细胞的免疫应答中起作用。虽然IL-12可强有力激活幼稚T细胞，但是最初的报道认为IL-23可优先作用于记忆T细胞，促进其分泌IFN-γ和增殖，这表明IL-23在控制细菌感染上有重要作用。IL-23被进一步描述为是一种控制周围组织炎症的关键细胞因子。p19的过表达与多个器官以及包含皮肤在内的上皮组织的炎症有关。IL-23参与中枢神经系统和自身免疫性疾病的炎症。

小鼠 Mouse Il23a 分子靶点信息

分子名：Il23a, interleukin 23, alpha subunit p19
别称：
- IL-23
- IL-23p19
- p19
基因序列：NCBI_Gene: 83430
蛋白序列：
- UniprotKB: Q9EQ14

小鼠 Mouse Il23a 靶点分子功能（预测）

Contributes to interleukin-23 receptor binding activity. Involved in positive regulation of defense response to virus by host; positive regulation of immune response; and positive regulation of neutrophil chemotaxis. Acts upstream of or within T cell proliferation and positive regulation of transcription by RNA polymerase II. Located in extracellular space. Part of interleukin-23 complex. Is expressed in decidua; decidua basalis; embryo; and extraembryonic component. Orthologous to human IL23A (interleukin 23 subunit alpha).