PMA/Ionomycin Mixture(250X)佛波酯/离子霉素混合物
¥460.00 – ¥2,060.00
在售SKU:70-CS1001-500, 70-CS1001-020, 70-CS1001
描述
1.产品简介
PMA/Ionomycin Mixture (250×)是佛波酯(Phorbol 12-Myristate 13-Acetate, PMA)和离子霉素(Ionomycin)的混合物。PMA和Ionomycin处理足以诱导很多类型的细胞活化,分泌细胞因子。该混合物可用于刺激体外培养细胞产生细胞因子,随后用免疫学方法进行检测。还可以与蛋白转运抑制剂(BFA/Monensin Mixture (250×) (目录号CS1002)联合使用,使诱导的细胞因子滞留在胞内。使用时,终浓度稀释至1×,即每250μl细胞培养基中加入1μl PMA/Ionomycin Mixture (250×)。
2.产品特点
•诱导细胞活化能力强
•浓度高,用前稀释
•操作简单
•常备现货
引用文献
文章目录[隐藏]
- Potential shared therapeutic and hepatotoxic mechanisms of Tripterygium wilfordii polyglycosides treating three kinds of autoimmune skin diseases by regulating IL-17 signaling pathway and Th17 cell differentiation 
- Casein Kinase II exacerbates rheumatoid arthritis via promoting Th1 and Th17 cell inflammatory responses 
- Peripheral Th17/Treg Cell-Mediated Immunity Imbalance in Allergic Rhinitis Patients 
- Mbd2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting Irf4 Expression 
- Immunologic Response to Tumor Ablation with Irreversible Electroporation 
- In-Situ Administration of Dendritic Cells Following Argon-Helium Cryosurgery Enhances Specific Antiglioma Immunity in Mice 
- Next Generation Sequencing for Mirna Profile of Spleen Cd4(+) T Cells in the Murine Model of Acute Asthma 
- Norisoboldine Ameliorates Dss-Induced Ulcerative Colitis in Mice through Induction of Regulatory T Cells in Colons 
- Deregulation of Regulatory T Cells in Acute-on-Chronic Liver Failure: A Rat Model 
- Jieduquyuziyin Prescription Suppresses Il-17 Production and Th17 Activity in Mrl/Lpr Mice by Inhibiting Expression of Ca(2+)/Calmodulin-Dependent Protein Kinase-4 
- Caveolin-1 Promotes the Imbalance of Th17/Treg in Patients with Chronic Obstructive Pulmonary Disease 
- Sinomenine Suppresses Collagen-Induced Arthritis by Reciprocal Modulation of Regulatory T Cells and Th17 Cells in Gut-Associated Lymphoid Tissues 
- Norisoboldine Ameliorates Collagen-Induced Arthritis through Regulating the Balance between Th17 and Regulatory T Cells in Gut-Associated Lymphoid Tissues 
- Mbd2 Regulates Differentiation and Function of Th17 Cells in Neutrophils- Dominant Asthma Via Hif-1α 
- The Role of Il-23/Th17 Pathway in Patients with Primary Immune Thrombocytopenia 
- Sceptridium Ternatum Extract Exerts Antiasthmatic Effects by Regulating Th1/Th2 Balance and the Expression Levels of Leukotriene Receptors in a Mouse Asthma Model 
- P2x7 Blockade Attenuates Murine Lupus Nephritis by Inhibiting Activation of the Nlrp3/Asc/Caspase 1 Pathway 
- 皮肤 皮肤损伤组织 组织匀浆 血清
Potential shared therapeutic and hepatotoxic mechanisms of Tripterygium wilfordii polyglycosides treating three kinds of autoimmune skin diseases by regulating IL-17 signaling pathway and Th17 cell differentiation 
- 细胞培养上清 血清
Casein Kinase II exacerbates rheumatoid arthritis via promoting Th1 and Th17 cell inflammatory responses 
Peripheral Th17/Treg Cell-Mediated Immunity Imbalance in Allergic Rhinitis Patients 
Mbd2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting Irf4 Expression 
Immunologic Response to Tumor Ablation with Irreversible Electroporation 
In-Situ Administration of Dendritic Cells Following Argon-Helium Cryosurgery Enhances Specific Antiglioma Immunity in Mice 
Next Generation Sequencing for Mirna Profile of Spleen Cd4(+) T Cells in the Murine Model of Acute Asthma 
Norisoboldine Ameliorates Dss-Induced Ulcerative Colitis in Mice through Induction of Regulatory T Cells in Colons 
Deregulation of Regulatory T Cells in Acute-on-Chronic Liver Failure: A Rat Model 
Jieduquyuziyin Prescription Suppresses Il-17 Production and Th17 Activity in Mrl/Lpr Mice by Inhibiting Expression of Ca(2+)/Calmodulin-Dependent Protein Kinase-4 
Caveolin-1 Promotes the Imbalance of Th17/Treg in Patients with Chronic Obstructive Pulmonary Disease 
Sinomenine Suppresses Collagen-Induced Arthritis by Reciprocal Modulation of Regulatory T Cells and Th17 Cells in Gut-Associated Lymphoid Tissues 
Norisoboldine Ameliorates Collagen-Induced Arthritis through Regulating the Balance between Th17 and Regulatory T Cells in Gut-Associated Lymphoid Tissues 
Mbd2 Regulates Differentiation and Function of Th17 Cells in Neutrophils- Dominant Asthma Via Hif-1α 
The Role of Il-23/Th17 Pathway in Patients with Primary Immune Thrombocytopenia 
Sceptridium Ternatum Extract Exerts Antiasthmatic Effects by Regulating Th1/Th2 Balance and the Expression Levels of Leukotriene Receptors in a Mouse Asthma Model 
P2x7 Blockade Attenuates Murine Lupus Nephritis by Inhibiting Activation of the Nlrp3/Asc/Caspase 1 Pathway 
Qin Z, Wang P-Y, Wan J-J, Zhang Y, Wei J, Sun Y and Liu X (2020) MicroRNA124-IL6R Mediates the Effect of Nicotine in Inflammatory Bowel Disease by Shifting Th1/Th2 Balance Toward Th1. Front. Immunol. 11:235. doi: 10.3389/fimmu.2020.00235
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2
Wan X, Pei W Y, Zhang L, et al. A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide–Autoreactive CD4+ and CD8+ T Cells[J]. The Journal of Immunology, 2019 (IF:4.5)
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3
Sun N, Wei X, Wang J, et al. Caveolin-1 Promotes the Imbalance of Th17/Treg in Patients with Chronic Obstructive Pulmonary Disease[J]. Inflammation, 2016, 39(6): 2008-2015 (IF:2.618)
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4
Liu Y, Chen Z, Xu K, et al. Next generation sequencing for miRNA profile of spleen CD4 +, T cells in the murine model of acute asthma[J]. Epigenomics, 2018 (IF:4.404)
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5
Xiaoxiang Li, Kui Xu, Wei Li, et al. Immunologic Response to Tumor Ablation with Irreversible Electroporation[J]. PLOS ONE, 2012, 7(11): e48749 (IF:4.092)
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6
Zhao J, Wang H, Dai C, et al. P2X7 blockade attenuates lupus nephritis by inhibiting NLRP3/ASC/caspase-1 activation[J]. Arthritis & Rheumatism, 2013 (IF:7.477)
查看原文
7
Yong Yuan, Bo Yang, Zuowu Ye, et al. Sceptridium ternatum extract exerts antiasthmatic effects by regulating Th1/Th2 balance and the expression levels of leukotriene receptors in a mouse asthma model[J]. J ETHNOPHARMACOL, 2013, 149: 701-706 (IF:2.755)
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8
Lin C, Wang Q, Lu G, et al. In-situ administration of dendritic cells following argon-helium cryosurgery enhances specific antiglioma immunity in mice[J]. Neuroreport, 2014, 25: 900-908 (IF:1.343)
查看原文
9
Lv Q, Qiao S M, Xia Y, et al. Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons[J]. International Immunopharmacology, 2015, 29(2) (IF:2.472)
查看原文
10
Tong Bei, Yu Juntao, Wang Ting, et al. Sinomenine suppresses collagen-induced arthritis by reciprocal modulation of regulatory T cells and Th17 cells in gut-associated lymphoid tissues[J]. Molecular Immunology, 2015, 65: 94-103 (IF:2.973)
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11
Tong Bei, Dou Yannong, Wang Ting, et al. Norisoboldine ameliorates collagen-induced arthritis through regulating the balance between Th17 and regulatory T cells in gut-associated lymphoid tissues[J]. Toxicology and Applied Pharmacology, 2015, 282: 90-99 (IF:3.705)
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12
Shui B, Xia W, Wen C, et al. Jieduquyuziyin prescription suppresses IL-17 production and Th17 activity in MRL/lpr mice by inhibiting expression of Ca2+/calmodulin-dependent protein kinase-4[J]. Journal of Natural Medicines, 2015, 69(3): 349-357 (IF:1.593)
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13
Ye X, Zhang L, Wang H, et al. The Role of IL-23/Th17 Pathway in Patients with Primary Immune Thrombocytopenia[J]. PLOS ONE, 2015, 10(1): e0117704 (IF:3.234)
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14
Shunlan N, Shanshan L, Naibin Y, et al. Deregulation of Regulatory T Cells in Acute-on-Chronic Liver Failure: A Rat Model[J]. Mediators of Inflammation, 2017, 2017: 1-10 (IF:3.418)
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15
Aijun J, Yueling W, Wenjin S, et al. MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression[J]. Mediators of Inflammation, 2017, 2017: 1-10 (IF:3.232)
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16
Li X, Sun W J, Jia A J, et al. MBD2 regulates differentiation and function of Th17 cells in neutrophils- dominant asthma via HIF-1α[J]. Journal of Inflammation, 2018, 15(1): 15 (IF:2.208)
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17
Xuekun Huang, Yulian Chen, Fucheng Zhang, et al. Peripheral Th17/Treg cell-mediated immunity imbalance in allergic rhinitis patients[J]. BRAZ J OTORHINOLAR, 2014, 80(2): 152-155 (IF:0.545)
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18
Wan X,et al.A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide–Autoreactive CD4+ and CD8+ T Cells[J].The Journal of Immunology,2019(IF=4.5)
查看原文
19
Yu H T, Jiang L L, Liu R Q, et al. Association between the ratio of aryl hydrocarbon receptor (AhR) in Th17 cells to AhR in Treg cells and SLE skin lesions[J]. International Immunopharmacology, 2019, 69: 257-262 (IF:3.361)
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