CD2 靶点信息

CD2 分子靶点信息概述

  • 分子名：CD2, CD2 molecule
  • 基因家族：CD molecules; V-set domain containing; C2-set domain containing; Ig-like cell adhesion molecule family
  • 曾用名：SRBC
  • 全称：CD2 antigen (p50), sheep red blood cell receptor

CD2 分子靶点综述

该 RPA-2.10抗体与人CD2反应，CD2是一种约 50kDa 糖蛋白，是Ig超家族的成员。CD2又称LFA-2，是CD58在人体内的受体，在80-90%的人外周血淋巴细胞、NK细胞的亚型和所有成熟的T细胞的表面表达。CD2在T细胞信号转导和淋巴细胞粘附中起着重要作用。

CD2, CD2 molecule 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human CD2 分子靶点信息

  • 分子名：CD2, CD2 molecule
  • 别称：
    • cd2 antigen
    • CD2 antigen (p50), sheep red blood cell receptor
    • erythrocyte receptor
    • FLJ46032
    • LFA-2
    • LFA-3 receptor
    • lymphocyte-function antigen-2
    • rosette receptor
    • SRBC
    • T-cell surface antigen CD2
    • T-cell surface antigen T11/Leu-5
    • T11
  • 基因序列：NCBI_Gene: 914
  • 蛋白序列：UniProtKB: P06729

人 Human CD2靶点分子功能（预测）

Enables signaling receptor binding activity. Involved in heterotypic cell-cell adhesion and positive regulation of cytokine production. Located in external side of plasma membrane.

小鼠 Mouse Cd2 分子靶点信息

小鼠 Mouse Cd2 靶点分子功能（预测）

Enables identical protein binding activity. Predicted to be involved in T cell activation; heterotypic cell-cell adhesion; and positive regulation of cytokine production. Located in several cellular components, including cell-cell junction; cytoplasmic side of plasma membrane; and external side of plasma membrane. Is anchored component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human CD2 (CD2 molecule).

大鼠 Rat Cd2 分子靶点信息

  • 分子名：Cd2, Cd2 molecule
  • 别称：
    • CD2 antigen
    • CD2R
    • LFA-2
    • LFA-3 receptor
    • LFA2
    • OX-34
    • OX-34 antigen
    • OX-45 surface antigen homolog to human T lymphocyte CD2 antigen
    • OX-45 surface antigen, homolog to human T lymphocyte CD2 antigen
    • OX34
    • T-cell surface antigen CD2
    • T-cell surface antigen T11/Leu-5
  • 基因序列：NCBI_Gene: 497761
  • 蛋白序列：UniProtKB: P08921

大鼠 Rat Cd2 靶点分子功能（预测）

Enables identical protein binding activity; protein self-association; and receptor tyrosine kinase binding activity. Involved in T cell activation and cell-cell adhesion. Located in cell surface and membrane raft. Part of protein-containing complex. Orthologous to human CD2 (CD2 molecule).

CD2 分子产品列表

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